TRIM5 Antibody

Western Blot: TRIM5 Antibody [NBP1-52607] - Western blot of TRIM5 expression in human bladder (A) and colon (B) cell lysate with TRIM5 antibody at 2 ug /ml.

Immunohistochemistry-Paraffin: TRIM5 Antibody [NBP1-52607] - Analysis of anti-TRIM5 antibody with human small intestine at concentration 5 ug/ml.

Immunohistochemistry-Paraffin: TRIM5 Antibody [NBP1-52607] - Analysis of anti-TRIM5 antibody with human pancreas at concentration 5 ug/ml.

Immunofluorescence: TRIM5 Antibody [NBP1-52607] - Immunofluorescence of TRIM5 gamma in human bladder tissue with TRIM5 gamma antibody at 20 ug/ml.

Product Discontinued

TRIM5 Antibody Summary

• Immunogen: A synthetic peptide corresponding to 15 amino acids near the C-terminus of human TRIM5 gamma. The immunogen is located within the last 50 amino acids of TRIM5 gamma.
• Specificity: Multiple isoforms of AIF are known to exist.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TRIM5
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100 - 1:2000
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 2.5 ug/ml
  • Western Blot 1-2 ug/ml
• Application Notes: A band at approximately 35 kDa can be detected in Western Blot. Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for TRIM5 Antibody

• EC 6.3.2
• EC 6.3.2.-
• RING finger protein 88
• RNF88
• RNF88tripartite motif protein TRIM
• TRIM5
• TRIM5alpha
• tripartite motif containing 5
• tripartite motif protein TRIM5
• tripartite motif-containing 5
• tripartite motif-containing protein 5

Background

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Five alternatively spliced transcript variants for this gene have been described. However, the full length nature of two of the variants has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TRIM5