Human TRAILR2/TNFRSF10B ELISA Kit (Colorimetric)

ELISA: Human TRAILR2/TNFRSF10B ELISA Kit (Colorimetric) [NBP3-14637] - Example of Human TRAILR2/TNFRSF10B Standard Curve.

• Reactivity: Hu
• Applications: ELISA
• Suitable Sample Type: Serum, Cell lysates, Cell culture supernatant
• Standard Curve Range: 31.25-1000 pg/ml
• Sensitivity: 6 pg/ml

Human TRAILR2/TNFRSF10B ELISA Kit (Colorimetric) Summary

• Description: Incubation: 2 hours 30 minutes
• Specificity: Specific for human TRAILR2/TNFRSF10B. No cross reactivity was observed with TRAIL, CD117, IL-6R, IL-2R, CD116, TRAIL R1, TRAIL R3, TRAIL R4, CD178 and Granzyme B..
• Standard Curve Range: 31.25-1000 pg/ml
• Sensitivity: 6 pg/ml
• Assay Type: Sandwich ELISA
• Inter-Assay: CV% < 7.4
• Intra-Assay: CV% < 3.2
• Spike Recovery: 83 to 124%
• Sample Volume: 100 ul
• Kit Type: ELISA Kit (Colorimetric)
• Gene: TNFRSF10B

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.

Alternate Names for Human TRAILR2/TNFRSF10B ELISA Kit (Colorimetric)

• CD262 antigen
• CD262
• death domain containing receptor for TRAIL/Apo-2L
• Death receptor 5
• DR5
• DR5TRICK2B
• Fas-like protein
• KILLER/DR5
• KILLERapoptosis inducing protein TRICK2A/2B
• TNF-related apoptosis-inducing ligand receptor 2
• TNFRSF10B
• TRAIL R2
• TRAIL receptor 2
• TRAILR2
• TRAIL-R2apoptosis inducing receptor TRAIL-R2
• TRAILR2cytotoxic TRAIL receptor-2
• TRICK2
• TRICK2A
• TRICKB
• tumor necrosis factor receptor superfamily member 10B
• tumor necrosis factor receptor superfamily, member 10b
• tumor necrosis factor receptor-like protein ZTNFR9
• ZTNFR9

Background

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family. DR4 was recently identified as the receptor for TRAIL. A novel death domain containing receptor for TRAIL was more recently identified and designated DR5, Apo2, TRAIL-R2, TRICK2, or KILLER by several groups independently (1-2). Like DR4, DR5 transcript is widely expressed in normal tissues and in many types of tumor cells. DR5 binds to TRAIL and mediates TRAIL induced cell death. Overexpression of DR5 induces apoptosis and activates NF-kB.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: TNFRSF10B