Recombinant Human TRAF3IP1 GST (N-Term) Protein

12.5% SDS-PAGE Stained with Coomassie Blue.

Product Discontinued

Recombinant Human TRAF3IP1 GST (N-Term) Protein Summary

• Description: A recombinant protein with a N-terminal GST tag corresponding to the amino acid sequence 592-690 of Human TRAF3IP1
  
  

  Source: Wheat Germ (in vitro)

  Amino Acid Sequence: TLCKSALPLGKIMDYIQEDVDAMQNELQMWHSENRQHAEALQQEQRITDCAVEPLKAELAELEQLIKDQQDKICAVKANILKNEEKIQKMVYSINLTSR

• Preparation Method: in vitro wheat germ expression system
• Details of Functionality: This protein was produced in an in vitro wheat germ expression system that should preserve correct conformational folding that is necessary for biological function. While it is possible that this protein could display some level of activity, the functionality of this protein has not been explicitly measured or validated.
• Source: Wheat germ
• Protein/Peptide Type: Partial Recombinant Protein
• Gene: TRAF3IP1
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunoaffinity Purification
  • Protein Array
  • Western Blot
• Theoretical MW: 36.63 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
• Preservative: No Preservative
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Recombinant Human TRAF3IP1 GST (N-Term) Protein

• DKFZp434F124
• Interleukin-13 receptor alpha 1-binding protein 1
• Microtubule-interacting protein associated with TRAF3
• microtubule-interacting protein that associates with TRAF3
• MIPT3interleukin 13 receptor alpha 1-binding protein-1
• MIP-T3microtubule interacting protein that associates with TRAF3
• TNF receptor-associated factor 3 interacting protein 1
• TRAF3-interacting protein 1

Background

MIP-T3 (microtubule-interacting protein associated with TRAF3) was originally identified in a yeast-two hybrid screen for proteins that interact with the tumor necrosis factor receptor (TNFR)-associated factor 3 (TRAF3). As a microtubule binding protein, MIP-T3 has been found to mediate the binding of DISC1 (disrupted-in-schizophrenia 1) to microtubules. MIP-T3 has also been shown to associate with IL13 receptor alpha (IL-13Ralpha1) and function as an inhibitor of IL-13 signaling. Recently, studies of the C. elegans homolog of MIP-T3 (DYF-11) have revealed that MIP-T3 is critical to cilium development; and in mammalian cells, MIP-T3 has been found to localize to basal bodies and cilia. Alternate names for MIP-T3 include TRAF3IP1, interleukin 13 receptor alpha1-binding protein 1, and TRAF3-interacting protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: TRAF3IP1