Recombinant Human TIMP-1 Protein

Product Discontinued

Recombinant Human TIMP-1 Protein Summary

• Description: Recombinant protein containing 184 amino acids for Human TIMP-1
  
  

  Source:Baculovirus (Sf9 insect cells)
  Amino Acid Sequence:( P01033)

• Preparation Method: Determined to be >92% pure by SDS-PAGE
• Source: Sf 9 (baculovirus)
• Protein/Peptide Type: Recombinant Protein
• Gene: TIMP1
• Purity: >92%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 28 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: 50 mM Tris-HCl (pH 7), 200 mM NaCl, 5 mM CaCl2, 1 uM ZnCl2, 0.05% Brij 35
• Preservative: 0.05% Sodium Azide
• Concentration: 0.05 mg/ml
• Purity: >92%, by SDS-PAGE

Alternate Names for Recombinant Human TIMP-1 Protein

• CLGI
• Collagenase inhibitor
• collagenase inhibitor)
• EPATIMP-1
• EPO
• erythroid potentiating activity
• Erythroid-potentiating activity
• Fibroblast collagenase inhibitor
• FLJ90373
• HCI
• metalloproteinase inhibitor 1
• TIMP metallopeptidase inhibitor 1
• TIMP1
• TIMP-1
• TIMPtissue inhibitor of metalloproteinase 1 (erythroid potentiating activity
• Tissue inhibitor of metalloproteinases 1

Background

The tissue inhibitor of metalloproteinases (TIMP-1) is a glycoprotein with a molecular mass of about 28 kDa. The secreted protein consists of 184 amino acids, six disuilfide bonds and two glycosylation sites containing N-linked oligosaccharides. TIMP-1 specifically inhibits the extracellular-matrix-egradingmetalloproteinases such as collagenase, gelatinase and stromelysin. It has no activity on mammalian membrane metallo-proteinases, procollagen peptidase, or on bacterial metalloproteinases such as thermolysin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: TIMP1