Thyroid receptor-interacting protein 11 Antibody (10G5) - Azide and BSA Free

Immunocytochemistry/Immunofluorescence: Thyroid receptor-interacting protein 11 Antibody (10G5) [NBP1-41204] - Analysis of methanol-fixed HeLa, using antibody at 1:100 dilution.

• Reactivity: Hu
• Applications: WB, ICC/IF, IP
• Clone: 10G5
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

Thyroid receptor-interacting protein 11 Antibody (10G5) - Azide and BSA Free Summary

• Description: Novus Biologicals Mouse Thyroid receptor-interacting protein 11 Antibody (10G5) - Azide and BSA Free (NBP1-41204) is a monoclonal antibody validated for use in WB, ICC/IF and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Amino acids 1099-1372 of Thyroid receptor-interacting protein 11 expressed in E. coli.
• Specificity: This antibody will recognize human TRIP230.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: TRIP11
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence Assay dependent
  • Immunoprecipitation Assay dependent
  • Western Blot 1:500
• Application Notes: ICC/IF, IP Assay dependent
• Theoretical MW: 228 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein G purified

Alternate Names for Thyroid receptor-interacting protein 11 Antibody (10G5) - Azide and BSA Free

• CEV14TR-interacting protein 11
• Clonal evolution-related gene on chromosome 14 protein
• GMAP-210ACG1A
• Golgi-associated microtubule-binding protein 210
• Golgi-microtubule-associated protein of 210 kDa
• thyroid hormone receptor interactor 11
• thyroid receptor-interacting protein 11
• TRIP-11
• Trip230

Background

The Trip230 gene encodes a protein of 1,978 amino acids with an estimated molecular mass of 230 kDa. The gene is located on chromosome 14q31, which is in a region associated with genetic alterations and thyroid hormone response abnormalities. The Trip230 protein interacts with Rb and thyroid hormone receptor (TR) using two distinct domains. Complex formation with Rb is in a hormone independent manner, but when Trip230 forms a complex with TR, it is in a thyroid hormone-dependent manner. After T3 treatment, Trip230 is phosphorylated and transported to the nucleus, suggesting that phosphorylation may be important for its nuclear translocation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TRIP11
• Entrez:
  • 9321(Human)