THOC5 Antibody


Western Blot: THOC5 Antibody [NBP2-20621] - Sample (30 ug of whole cell lysate) A: 293T B: A431 C: HeLa 7. 5% SDS PAGE gel, diluted at 1:1000.
Immunohistochemistry-Paraffin: THOC5 Antibody [NBP2-20621] - Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using antibody at 1:500 dilution.

Product Details

Reactivity HuSpecies Glossary
Applications WB, IHC, IHC-P
0.6 mg/ml

Order Details

THOC5 Antibody Summary

Recombinant protein fragment contain a sequence corresponding to a region within amino acids 308 and 641 (Q13769) of THOC5
Nucleus (By similarity); Cytoplasm (By similarity)
Predicted Species
Mouse (94%), Rat (94%), Bovine (95%)
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Store at -20C. Avoid freeze-thaw cycles.
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7).
0.01% Thimerosal
0.6 mg/ml
Immunogen affinity purified


  • Western Blot 1:500-1:3000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
Application Notes
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
79 kDa

Reactivity Notes

Human. Species reactivity based on sequence identity: Mouse (94%), Chicken (84%), Rat (94%), Bovine (95%)

Alternate Names for THOC5 Antibody

  • C22orf19
  • chromosome 22 open reading frame 19
  • Fmip
  • Fms-interacting protein
  • fSAP79hTREX90
  • Functional spliceosome-associated protein 79
  • KIAA0983
  • NF2/meningioma region protein pK1.3
  • PK1.3
  • Placental protein 39.2
  • PP39.2
  • THO complex 5
  • THO complex subunit 5 homolog


Component the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between THOC4 and the cap-binding protein NCBP1. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The recruitment of the TREX complex to the intronless viral mRNA occurs via an interaction beteen KSHV ORF57 protein and THOC4. UAP56 functions as a bridge between THOC4 and the THO complex. THOC5 in conjunction with THOC4 functions in NXF1-NXT1 mediated nuclear export of HSP70 mRNA. May be involved in the differentiation of granulocytes and adipocytes.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies


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Contact Information

Product PDFs


Gene Symbol THOC5

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