Thioredoxin-2 Antibody - BSA Free

Immunocytochemistry/Immunofluorescence: Thioredoxin-2 Antibody [NBP1-92499] - Staining of human cell line A-431 shows positivity in mitochondria.

Immunohistochemistry-Paraffin: Thioredoxin-2 Antibody [NBP1-92499] - Staining of human adrenal gland shows strong granular cytoplasmic positivity in glandular cells.

• Reactivity: Hu, Mu
• Applications: ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Thioredoxin-2 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Thioredoxin-2 Antibody - BSA Free (NBP1-92499) is a polyclonal antibody validated for use in IHC and ICC/IF. Anti-Thioredoxin-2 Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: LTSRALQTPQCSPGGLTVTPNPARTIYTTRISLTTFNIQDGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLKKL
• Predicted Species: Mouse (91%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TXN2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF,Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  Thioredoxin-2 Protein (NBP1-92499PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (89%)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Thioredoxin-2 Antibody - BSA Free

• mitochondrial thioredoxin
• MTRX
• MT-TRX
• thioredoxin 2
• thioredoxin, mitochondrial
• Thioredoxin2
• Thioredoxin-2
• Trx2
• TXN2

Background

This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Thioredoxin-2 Antibody (NBP1-92499)(2)

Publications using NBP1-92499

• Karmi O, Sohn YS, Zandalinas SI et al. Disrupting CISD2 function in cancer cells primarily impacts mitochondrial labile iron levels and triggers TXNIP expression Free Radical Biology and Medicine 2021-11-01 [PMID: 34547371]
• Dammeyer P, Arner ES., et al. Human Protein Atlas of redox systems - What can be learnt? Biochim Biophys Acta 2010-07-18 [PMID: 20647035]

Bioinformatics

• Gene Symbol: TXN2