THAP1 Antibody (2C1-2F2)

Western Blot: THAP1 Antibody (2C1-2F2) [H00055145-M01] - Analysis of THAP1 over-expressed 293 cell line, cotransfected with THAP1 Validated Chimera RNAi ( Cat # H00055145-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with THAP1 monoclonal antibody (M01), clone 2C1-2F2 (Cat # H00055145-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.

Immunocytochemistry/Immunofluorescence: THAP1 Antibody (2C1-2F2) [H00055145-M01] - Analysis of monoclonal antibody to THAP1 on HeLa cell. Antibody concentration 10 ug/ml.

Western Blot: THAP1 Antibody (2C1-2F2) [H00055145-M01] - Analysis of THAP1 expression in transfected 293T cell line by THAP1 monoclonal antibody (M01), clone 2C1-2F2.Lane 1: THAP1 transfected lysate(24.9 KDa).Lane 2: Non-transfected lysate.

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF, RNAi
• Clone: 2C1-2F2
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

THAP1 Antibody (2C1-2F2) Summary

• Immunogen: THAP1 (AAH21721, 1 a.a. ~ 213 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MVQSCSAYGCKNRYDKDKPVSFHKFPLTRPSLCKEWEAAVRRKNFKPTKYSSICSEHFTPDCFKRECNNKLLKENAVPTIFLCTEPHDKKEDLLEPQEQLPPPPLPPPVSQVDAAIGLLMPPLQTPVNLSVFCDHNYTVEDTMHQRKRIHQLEQQVEKLRKKLKTAQQRCRRQERQLEKLKEVVHFQKEKDDVSERGYVILPNDYFEIVEVPA
• Specificity: THAP1 - THAP domain containing, apoptosis associated protein 1
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: THAP1
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500
  • ELISA
  • Immunocytochemistry/Immunofluorescence
  • RNA Inhibition
• Application Notes: Antibody Reactive against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control. It has also been used for RNAi Validation.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for THAP1 Antibody (2C1-2F2)

• 4833431A01Rik
• dystonia 6, torsion (autosomal dominant)
• DYT6
• FLJ10477
• MGC33014
• nuclear proapoptotic factor
• THAP domain containing, apoptosis associated protein 1
• THAP domain protein 1
• THAP domain-containing protein 1

Background

The protein encoded by this gene contains a THAP domain, a conserved DNA-binding domain. This protein colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies, and functions as a proapoptotic factor that links PAWR to PML nuclear bodies. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: THAP1
• Entrez:
  • 55145(Human)
• OMIM:
  • 609520(Human)
• Uniprot:
  • AAH21721(Human)