TFB2M Antibody

Western Blot: TFB2M Antibody [H00064216-B01P] - Analysis of TFB2M expression in A-431.

Western Blot: TFB2M Antibody [H00064216-B01P] - Analysis of TFB2M expression in transfected 293T cell line by TFB2M polyclonal antibody. Lane 1: TFB2M transfected lysate(43.56 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

TFB2M Antibody Summary

• Immunogen: TFB2M (NP_071761.1, 1 a.a. - 396 a.a.) full-length human protein. MWIPVVGLPRRLRLSALAGAGRFCILGSEAATRKHLPARNHCGLSDSSPQLWPEPDFRNPPRKASKASLDFKRYVTDRRLAETLAQIYLGKPSRPPHLLLECNPGPGILTQALLEAGAKVVALESDKTFIPHLESLGKNLDGKLRVIHCDFFKLDPRSGGVIKPPAMSSRGLFKNLGIEAVPWTADIPLKVVGMFPSRGEKRALWKLAYDLYSCTSIYKFGRIEVNMFIGEKEFQKLMADPGNPDLYHVLSVIWQLACEIKVLHMEPWSSFDIYTRKGPLENPKRRELLDQLQQKLYLIQMIPRQNLFTKNLTPMNYNIFFHLLKHCFGRRSATVIDHLRSLTPLDARDILMQIGKQEDEKVVNMHPQDFKTLFETIERSKDCAYKWLYDETLEDR
• Specificity: TFB2M - transcription factor B2, mitochondrial,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: TFB2M
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500
• Application Notes: Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for TFB2M Antibody

• dimethyladenosine transferase 2, mitochondrial
• EC 2.1.1.-
• FLJ22661
• FLJ23182
• HCV NS5A-transactivated protein 5
• Hepatitis C virus NS5A-transactivated protein 5
• Hkp1
• h-mtTFB
• h-mtTFB2
• hTFB2M
• Mitochondrial 12S rRNA dimethylase 2
• Mitochondrial transcription factor B2
• mtTFB2
• NS5ATP5
• S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2
• transcription factor B2, mitochondrial

Background

S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA atthe conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction withPOLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, itactivates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TFB2M
• Entrez:
  • 64216(Human)
• Uniprot:
  • NP_071761.1(Human)