TFB2M Products

Description

S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA atthe conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction withPOLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, itactivates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity

Bioinformatics

Entrez	64216 Human
Uniprot	NM_022366 Human NP_071761 Human NP_071761.1 Human Q9H5Q4 Human
Product By Gene ID	64216
Alternate Names	NS5ATP5 h-mtTFB EC 2.1.1.- Mitochondrial transcription factor B2 dimethyladenosine transferase 2, mitochondrial Mitochondrial 12S rRNA dimethylase 2 S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2 Hepatitis C virus NS5A-transactivated protein 5 mtTFB2 Hkp1 HCV NS5A-transactivated protein 5 FLJ23182 hTFB2M FLJ22661 h-mtTFB2 transcription factor B2, mitochondrial

Diseases related to TFB2M

Discover more about diseases related to TFB2M.

Cardiomyopathies
Liver Diseases
Mitochondrial Dna Depletion
Non-neoplastic Disorder
Infarction
Multiple Organ Failure
Mitochondrial Diseases
Cardiac Hypertrophy
Premature Aging Syndrome
Parkinson Disease
Nonalcoholic Fatty Liver Disease
Endometriosis, Site Unspecified
Myocardial Infarction
Malignant Neoplasms
Cachexia
Dwarfism
Fatty Liver
Complete Hearing Loss
Glioblastoma

Pathways for TFB2M

View related products by pathway and learn more about each of the pathways below.

Translation
Aging
Mitochondrial Translation
Dna Replication
Oxidative Phosphorylation
Mitochondrial Dna Replication
Cell Differentiation
Localization
Methylation
Cell Death
Cell Growth
Glycolysis
Transport
Protein Phosphorylation
Programmed Cell Death
Electron Transport
Electron Transport Chain
Proteolysis
Vasculogenesis
Ribosome Assembly

PTMs for TFB2M

Learn more about PTMs related to TFB2M.

Methylation
Phosphorylation

Bioinformatics Tool for TFB2M

Discover related pathways, diseases and genes to TFB2M. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.