TFB2M Products

Description

S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA atthe conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction withPOLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, itactivates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity

Bioinformatics

Entrez	64216 Human
Uniprot	NM_022366 Human NP_071761 Human NP_071761.1 Human Q9H5Q4 Human
Product By Gene ID	64216
Alternate Names	dimethyladenosine transferase 2, mitochondrial EC 2.1.1.- FLJ22661 FLJ23182 HCV NS5A-transactivated protein 5 Hepatitis C virus NS5A-transactivated protein 5 Hkp1 h-mtTFB h-mtTFB2 hTFB2M Mitochondrial 12S rRNA dimethylase 2 Mitochondrial transcription factor B2 mtTFB2 NS5ATP5 S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2 transcription factor B2, mitochondrial