TERT Antibody Pack

Images

 
Immunohistochemistry-Paraffin: TERT Antibody Pack [NB100-913] - TERT was detected in immersion fixed paraffin-embedded sections of human liver cancer using anti-human mouse monoclonal antibody (Catalog # NB100-297) at ...read more
Western Blot: TERT Antibody Pack [NB100-913] - Increased levels of IFI16 protein in WI-38 cells reduce hTERT levels and inhibit telomerase activity. Total protein extracts prepared from WI-38 cells, either transfected ...read more
Immunohistochemistry-Paraffin: TERT Antibody Pack [NB100-913] - Normal human pancreas showing moderate TERT staining of exocrine cells and a subset of islets of Langerhans using TERT antibody (NB100-317).

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, IP, ChIP, KD

Order Details

TERT Antibody Pack Summary

Description
This pack contains 1 vial each of: NB100-317 (0.1 mL) and NB100-297 (0.1 mL).
Immunogen
See individual datasheets
Gene
TERT

Applications/Dilutions

Dilutions
  • Chromatin Immunoprecipitation (ChIP)
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Knockdown Validated
  • Western Blot
Application Notes
See individual datasheets of components for their validated applications
Publications
Read Publications using
NB100-913 in the following applications:

  • WB
    1 publication

Reactivity Notes

See individual datasheets of components for their validated species

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Kit Components

Alternate Names for TERT Antibody Pack

  • EST2Telomerase-associated protein 2
  • hEST2
  • hTERT
  • TCS1EC 2.7.7.49
  • Telomerase catalytic subunit
  • telomerase reverse transcriptase
  • TERT
  • TP2HEST2
  • TRTEC 2.7.7

Background

Telomeres are nucleoprotein structures at the ends of eukaryotic chromosomes. They regulate several crucial cellular functions and participate in the control of complex phenotypes, such as aging and cancer. Cell immortalization is strongly associated with the stabilization of telomere length. Therefore, it is suggested that cancer cells achieve immortalization in part through illegitimate activation of telomerase expression. hTERT is the rate-limiting catalytic subunit of telomerase. Telomerase (TERT) is an enzyme uniquely associated with immortal cell lines and is useful for identifying undifferentiated PSCs.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Packs are guaranteed for 1 year from date of receipt.

Publications for TERT Antibody Pack (NB100-913)(3)

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Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for TERT Antibody Pack (NB100-913) (0)

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Additional TERT Products

Research Areas for TERT Antibody Pack (NB100-913)

Find related products by research area.

Blogs on TERT.

Losing memory: Toxicity from mutant APP and amyloid beta explain the hippocampal neuronal damage in Alzheimer's disease
 By Jamshed Arslan Pharm.D.  Alzheimer's disease (AD) is an irreversible brain disorder that destroys memory and thinking skills. The telltale signs of AD brains are extracellular deposits of amy...  Read full blog post.

Reversing Cancer with Telomerase Reverse Transcriptase (TERT)
Telomerase reverse transcriptase (TERT) is a ribonucleoprotein enzyme essential for eukaryotic chromosomal termini replication. It is a useful marker as it is active only in progenitor and most cancer cells, but inactive or (active at very low activit...  Read full blog post.

Featured Product Citation using Novus' hTERT Antibody
In December 2009, researchers at the University of Southern California cited using Novus’ mouse monoclonal Telomerase Reverse Transcriptase Antibody (cat# NB100-317) [PMID: 19923445]. Specifically, Novus’ hTERT antibody was used for immunofluorescent ...  Read full blog post.

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Bioinformatics

Gene Symbol TERT