TAPBPR Antibody - BSA Free

Immunohistochemistry-Paraffin: Tapasin Related Protein Antibody [NBP1-87922] - Staining of human pancreas shows very weak cytoplasmic positivity in exocrine glandular cells.

Immunohistochemistry-Paraffin: Tapasin Related Protein Antibody [NBP1-87922] - Staining of human fallopian tube shows moderate cytoplasmic positivity in glandular cells.

Immunohistochemistry-Paraffin: Tapasin Related Protein Antibody [NBP1-87922] - Staining of human small intestine shows moderate cytoplasmic positivity in glandular cells.

Immunohistochemistry-Paraffin: Tapasin Related Protein Antibody [NBP1-87922] - Staining of human prostate shows weak cytoplasmic positivity in glandular cells.

Analysis in control (vector only transfected HEK293T lysate) and TAPBPL over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells).

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

TAPBPR Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit TAPBPR Antibody - BSA Free (NBP1-87922) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: LTIQDEGTYICQITTSLYRAQQIIQLNIQASPKVRLSLANEALLPTLICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSSLRQSVAGTYSISSSLTAEPGSAGATYTCQVTHISLEEPLGASTQVVPP
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TAPBPL
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
  • Western Blot 0.04-0.4 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  TAPBPR Recombinant Protein Antigen (NBP1-87922PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for TAPBPR Antibody - BSA Free

• FLJ10143
• TAP binding protein-like
• Tapasin Related Protein/TAPBPR
• Tapasin-like
• TAPASIN-R
• tapasin-related protein
• TAP-binding protein-like
• TAP-binding protein-related protein
• TAPBPL
• TAPBPR
• TAPBP-RTAP binding protein related
• TAPBPRtapasin-like

Background

Tapasin Related Protein encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TAPBPL