TAP2 Antibody (998524) [FITC]

• Reactivity: Hu
• Applications: WB, IHC, ICC/IF
• Clone: 998524
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: FITC

TAP2 Antibody (998524) [FITC] Summary

• Immunogen: Synthetic peptide containing human TAP2
  Accession # Q03519
• Specificity: Detects human TAP2 in direct ELISAs.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A or G purified from ascites

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from ascites

Alternate Names for TAP2 Antibody (998524) [FITC]

• ABC18
• ABCB3
• ABCB3ABC18
• antigen peptide transporter 2
• APT2
• ATP-binding cassette, sub-family B (MDR/TAP), member 3
• D6S217E
• MHC 2
• Peptide transporter involved in antigen processing 2
• Peptide transporter PSF2
• Peptide transporter TAP2
• PSF2
• PSF2PSF-2
• Really interesting new gene 11 protein
• RING11
• RING11ATP-binding cassette sub-family B member 3
• TAP2
• transporter 2, ABC (ATP binding cassette)
• transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
• Y1

Background

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces two products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.