SYPL1 Antibody - BSA Free

Western Blot: SYPL1 Antibody [NBP1-76316] - Human brain tissue lysate with SYPL1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

SYPL1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit SYPL1 Antibody - BSA Free (NBP1-76316) is a polyclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human SYPL1. The immunogen is located within the first 50 amino acids of SYPL1. Amino Acid Squence: APNIYLVRQRISRLGQ
• Specificity: This antibody will not recognize synaptophysin of SYPL2. Two isoforms of SYPL1 are known to exist; this antibody will only recognize the longer isoform.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SYPL1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1 ug/ml
• Control Peptide:

  SYPL1 Peptide (NBP1-76316PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for SYPL1 Antibody - BSA Free

• H-SP1
• pantophysin
• synaptophysin-like 1
• synaptophysin-like protein 1
• synaptophysin-like protein
• SYPL

Background

The synaptophysin-like protein 1, also known as pantophysin, is a homolog of the neuroendocrine-specific protein synaptophysin, with the highest level of homology across its four transmembrane domains. Unlike synaptophysin however, SYPL1 is ubiquitously expressed and found in small cytoplasmic transport vesicles regardless of their content. SYPL1 is thought to play a multifunctional role in vesicle biogenesis and transport and is a component of adipocyte transport vesicles, and thus may be involved in adipocyte secretion. SYPL1 also interacts with vesicle-associated membrane protein 2 (VAMP-2) in adipocytes and associates with GLUT4-containing vesicles. This antibody will not recognize synaptophysin of SYPL2. Two isoforms of SYPL1 are known to exist; this antibody will only recognize the longer isoform.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SYPL1
• Uniprot:
  • NP_006745(Human)