Syntaxin-BP1 Antibody

Western Blot: Syntaxin-BP1 Antibody [H00006812-D01P] - Analysis of STXBP1 expression in mouse spleen.

Western Blot: Syntaxin-BP1 Antibody [H00006812-D01P] - Analysis of STXBP1 expression in transfected 293T cell line by STXBP1 polyclonal antibody.Lane 1: STXBP1 transfected lysate(68.70 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

Syntaxin-BP1 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: STXBP1 (NP_003156.1, 1 a.a. - 603 a.a.) full-length human protein. MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVEDINKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVKSRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLCATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPSSPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTPIIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPRLIIFILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPTKFLMDLRHPDFRESSRVSFEDQAPTME
• Specificity: STXBP1 - syntaxin binding protein 1,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: STXBP1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Syntaxin-BP1 Antibody

• EIEE4
• FLJ37475
• hUNC18
• MUNC18-1
• NSEC1
• N-Sec1
• p67
• Protein unc-18 homolog 1
• Protein unc-18 homolog A
• rbSec1
• STXBP1
• syntaxin binding protein 1
• syntaxin-binding protein 1
• SyntaxinBP1
• Syntaxin-BP1
• UNC18
• unc18-1
• UNC18A
• unc-18A
• UNC18neuronal SEC1

Background

Munc-18 (mammalian homologue of Unc-18) is a protein that is thought to be involved in regulating exocytosis due, at least in part to its ability to bind syntaxin (Ciufo et al., 2005). Munc18-1 is a neuron-specific member of the Sec1/Munc18 protein family that binds to syntaxin1A and is thought to stabilize the complex (Liu et al., 2004). The function of Munc-18 is thought to be regulated by PKC phosphorylation of Ser515 on the Munc-18 protein (Sassa et al., 1996).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: STXBP1
• Entrez:
  • 6812(Human)
• Uniprot:
  • NP_003156.1(Human)