Synaptogyrin 1 Antibody

Images

 
Western Blot: Synaptogyrin 1 Antibody [NBP1-77371] - Rat brain tissue lysate with SYNGR1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
Immunocytochemistry/ Immunofluorescence: Synaptogyrin 1 Antibody [NBP1-77371] - Immunofluorescence of SYNGR1 in rat brain tissue with SYNGR1 antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: Synaptogyrin 1 Antibody [NBP1-77371] - Rat brain tissue with SYNGR1 antibody at 2.5 ug/mL.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

Synaptogyrin 1 Antibody Summary

Immunogen
Antibody was raised against a 16 amino acid synthetic peptide from near the center of human SYNGR1. The immunogen is located within amino acids 120 - 170 of SYNGR1.
Marker
Synaptic Vesicle Marker
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SYNGR1
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 20 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Control Peptide
Synaptogyrin 1 Peptide (NBP1-77371PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Synaptogyrin 1 Antibody

  • MGC1939
  • synaptogyrin 1
  • synaptogyrin-1

Background

Synaptogyrins comprise a family of tyrosine-phosphorylated membrane proteins with two neuronal (SYNGR1 and SYNGR3) and one ubiquitous (SYNGR2) members. SYNGR1 and -3 are synaptic vesicle proteins, residing in some cases on the same synaptic vesicle, and are thought to be involved in the regulation of neurotransmitter release. SYNGR2, by contrast, is absent from synaptic vesicles. The role and localization of a fourth synaptogyrin, SYNGR4, is unclear. The gene for SYNGR1is located at chromosome 22q13, a region linked to schizophrenia; however, there is mixed evidence suggesting that mutations in SYNGR1 might be associated with schizophrenia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol SYNGR1
Uniprot