SWAP70 Antibody (683317) [Janelia Fluor® 646]

• Reactivity: Hu, Mu
• Applications: WB
• Clone: 683317
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 646

SWAP70 Antibody (683317) [Janelia Fluor® 646] Summary

• Immunogen: E. coli-derived recombinant human SWAP70
  Arg386-Glu585
  Accession # Q9UH65
• Specificity: Detects human SWAP70 in direct ELISAs.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: SWAP70
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for SWAP70 Antibody (683317) [Janelia Fluor® 646]

• KIAA0640SWAP-70FLJ39540
• SWAP switching B-cell complex 70kDa subunit
• SWAP70
• switch-associated protein 70

Background

Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SWAP70