SUMO2 Antibody (SUMO2/1199) [Alexa Fluor™ Plus 680]

• Reactivity: Hu, Rt
• Applications: Flow, ICC/IF, IHC, CyTOF-ready, ICC/IF
• Clone: SUMO2/1199
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 680

SUMO2 Antibody (SUMO2/1199) [Alexa Fluor™ Plus 680] Summary

• Immunogen: Recombinant human SUMO2 protein (Uniprot: P55854)
• Localization: Nuclear
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: SUMO2
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Predicted to show a broad species reactivity.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for SUMO2 Antibody (SUMO2/1199) [Alexa Fluor™ Plus 680]

• HSMT3
• MGC117191
• sentrin 2
• Sentrin-2
• small ubiquitin-like modifier 2
• small ubiquitin-related modifier 2
• SMT3 (suppressor of mif two 3, yeast) homolog 2
• SMT3 homolog 2
• SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
• SMT3 suppressor of mif two 3 homolog 2 (yeast)
• SMT3A
• SMT3B
• SMT3H2
• SUMO2
• SUMO-2
• SUMO3
• SUMO-3
• Ubiquitin-like protein SMT3A
• ubiquitin-like protein SMT3B

Background

Function: Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4; Subcellular location: Nucleus

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SUMO2