SUMO2/3 Antibody (SM23/496) [DyLight 755]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P
Clone
SM23/496
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 755

Order Details

SUMO2/3 Antibody (SM23/496) [DyLight 755] Summary

Immunogen
Recombinant human SUMO2 protein
Localization
Nuclear (SUMO-2); Cytoplasmic (SUMO-3)
Specificity
This MAb reacts with both SUMO-2 and SUMO-3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, 2 and 3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2 and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1, 2 and 3 proteins localize to the nuclear membrane, nuclear bodies and cytoplasm, respectively. SUMO-1 utilizes Ubc9 for conjugation to several target proteins, which include MDM2, p53, PML and RanGap1. SUMO-2 and 3 contribute to a greater percentage of protein modification than does SUMO-1 and unlike SUMO-1, they can form polymeric chains. In addition, SUMO-3 regulates beta-Amyloid generation and may be critical in the onset or progression of Alzheimer's disease.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
SUMO2
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin

Reactivity Notes

Shows broad species reactivity

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for SUMO2/3 Antibody (SM23/496) [DyLight 755]

  • HSMT3
  • small ubiquitin-like modifier 2
  • SMT3A
  • SMT3B
  • SMT3H2
  • SUMO2
  • SUMO2/3
  • SUMO3

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for SUMO2/3 Antibody (NBP2-34717IR) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-34717AF350
Alexa Fluor 405 NBP2-34717AF405
Alexa Fluor 488 NBP2-34717AF488
Alexa Fluor 532 NBP2-34717AF532
Alexa Fluor 594 NBP2-34717AF594
Alexa Fluor 647 NBP2-34717AF647
Alexa Fluor 700 NBP2-34717AF700
Alexa Fluor 750 NBP2-34717AF750
Allophycocyanin NBP2-34717APC
Allophycocyanin/Cy7 NBP2-34717APCCY7
Biotin NBP2-34717B
DyLight 350 NBP2-34717UV
DyLight 405 NBP2-34717V
DyLight 488 NBP2-34717G
DyLight 550 NBP2-34717R
DyLight 594 NBP2-34717DL594
DyLight 650 NBP2-34717C
DyLight 680 NBP2-34717FR
DyLight 755 NBP2-34717IR
HRP NBP2-34717H
Janelia Fluor 549 NBP2-34717JF549
Janelia Fluor 646 NBP2-34717JF646
PE NBP2-34717PE
PE/Atto594 NBP2-34717PEATT594
PE/Cy5.5 NBP2-34717PECY55
PE/Cy7 NBP2-34717PECY7

Additional SUMO2/3 Products

Array NBP2-34717IR

Bioinformatics Tool for SUMO2/3 Antibody (NBP2-34717IR)

Discover related pathways, diseases and genes to SUMO2/3 Antibody (NBP2-34717IR). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for SUMO2/3 Antibody (NBP2-34717IR)

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Pathways for SUMO2/3 Antibody (NBP2-34717IR)

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PTMs for SUMO2/3 Antibody (NBP2-34717IR)

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Blogs on SUMO2/3

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Bioinformatics

Gene Symbol SUMO2