STK39 Antibody

Western Blot: STK39 Antibody [NBP1-51955] - Staining (0.3ug/ml) of Human Cerebellum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Immunohistochemistry: STK39 Antibody [NBP1-51955] - (6ug/ml) staining of paraffin embedded Human Testis. Heat induced antigen retrieval with citrate buffer pH 6, HRP-staining.

Control: STK39 Antibody [NBP1-51955] - Negative Control showing staining of paraffin embedded Human Testis, with no primary antibody.

• Reactivity: Hu, Mu, Rt, Ca
• Applications: WB, ELISA, IHC, Ctrl
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

STK39 Antibody Summary

• Description: Novus Biologicals Goat STK39 Antibody (NBP1-51955) is a polyclonal antibody validated for use in IHC, WB and ELISA. Anti-STK39 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Peptide with sequence C-SQEKSRRVKEENPE corresponding to internal region according to NP_037365.2.
• Epitope: C-SQEKSRRVKEENPE
• Predicted Species: Mouse (100%), Rat (100%), Canine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: STK39
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Control
  • Immunohistochemistry 6.0 ug/ml
  • Peptide ELISA Detection limit 1:4000
  • Western Blot 0.3 - 1 ug/ml
• Application Notes: WB: Approx. 65 kDa band observed in human brain (cerebellum) lysates and in Jurkat lysates (calculated MW of 59.5 kDa band according to NP_037365.2).

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for STK39 Antibody

• DCHTsmall intestine SPAK-like kinase
• DKFZp686K05124
• EC 2.7.11
• EC 2.7.11.1
• PASK
• proline-alanine-rich STE20-related kinase
• serine threonine kinase 39
• Serine/threonine-protein kinase 39
• SPAKserine threonine kinase 39 (STE20/SPS1 homolog, yeast)
• STE20/SPS1 homolog
• STE20/SPS1-related proline-alanine-rich protein kinase
• Ste20-like protein kinase
• Ste-20-related kinase

Background

This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for STK39 Antibody (NBP1-51955)(1)

Publication using NBP1-51955

• Ramoz N, Cai G, Reichert JG et al. An analysis of candidate autism loci on chromosome 2q24-q33: evidence for association to the STK39 gene. Am J Med Genet B Neuropsychiatr Genet 2008-10-05 [PMID: 18348195]

Bioinformatics

• Gene Symbol: STK39
• Entrez:
  • 27347(Human)
  • 53416(Mouse)
  • 54348(Rat)
• Uniprot:
  • NP_037365.2(Human)