STEP Antibody Pair

Product Discontinued

STEP Antibody Pair Summary

• Description: Quality control test: Standard curve using recombinant protein (H00084867-P01) as an analyte. This antibody pair set comes with matched antibody pair to detect and quantify protein level of human PTPN5.
  
  
• Capture antibody: rabbit MaxPab affinity purified polyclonal anti-PTPN5 (100 ug)
• Detection antibody: mouse polyclonal anti-PTPN5 (40 ul)
• Standard Curve Range: 3 ng/ml to 100 ng/ml
• Assay Type: Sandwich ELISA
• Clonality: Monoclonal
• Gene: PTPN5

Applications/Dilutions

• Dilutions:
  • Sandwich ELISA 3 ng/ml - 100 ng/ml

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 1x PBS, pH 7.4
• Preservative: No Preservative

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for STEP Antibody Pair

• EC 3.1.3.48
• FLJ14427
• Neural-specific protein-tyrosine phosphatase
• protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
• protein-tyrosine phosphatase striatum-enriched
• PTPN5
• STEP
• STEPPTPSTEP
• Striatum-enriched protein-tyrosine phosphatase
• tyrosine-protein phosphatase non-receptor type 5

Background

The protein tyrosine phosphatase non-receptor type 5 or striatum-enriched protein-tyrosine phosphatase (STEP) protein is part of a family of protein tyrosine phosphatases enriched within the CNS, and is a key component of the NMDAR complex. It is expressed within dopaminoceptive neurons in the CNS and particularly enriched within the basal ganglia and related structures. STEP61 is the membrane-associated isoform and STEP46 is the cytosolic protein. In response to transient hypoxia-ischemia in the brain, STEP61 is proteolytically cleaved by calpain, thereby releasing a smaller isoform, STEP33.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: PTPN5