STEAP3/TSAP6 Antibody - BSA Free

STEAP3/TSAP6 Antibody [NBP2-20510] - HepG2 whole cell and cytoplasm extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with this antibody diluted at 1:1000. HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

STEAP3/TSAP6 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit STEAP3/TSAP6 Antibody - BSA Free (NBP2-20510) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human STEAP3/TSAP6. The exact sequence is proprietary.
• Localization: Endosome membrane; Multi-pass membrane protein (By similarity)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: STEAP3
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:3000
• Theoretical MW: 55 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Mouse (88%), Rat (87%), Bovine (85%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS, 20% Glycerol
• Preservative: 0.025% Proclin 300
• Purity: Antigen Affinity-purified

Alternate Names for STEAP3/TSAP6 Antibody - BSA Free

• AHMIO2
• dudlin 2
• Dudlin-2
• dudulin 2
• dudulin-2
• Dudulin-2,1010001D01Rik
• EC 1.16.1.-
• hpHyde
• hTSAP6
• metalloreductase STEAP3
• pHyde
• six transmembrane prostate protein 3
• Six-transmembrane epithelial antigen of prostate 3
• STEAP family member 3
• STEAP3
• STMP3
• TSAP6
• TSAP6STMP3
• tumor suppressor pHyde
• Tumor suppressor-activated pathway protein 6

Background

Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NAD(+) as acceptor (By similarity). May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: STEAP3
• Uniprot:
  • Q658P3(Human)