STEAP3/TSAP6 Antibody

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Western Blot: STEAP3/TSAP6 Antibody [NBP2-20510] - Sample (30 ug of whole cell lysate) A: HepG2 10% SDS PAGE gel, diluted at 1:1000.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

STEAP3/TSAP6 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human STEAP3. The exact sequence is proprietary.
Localization
Endosome membrane; Multi-pass membrane protein (By similarity)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
STEAP3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
Theoretical MW
55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Mouse (88%), Rat (87%), Bovine (85%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for STEAP3/TSAP6 Antibody

  • AHMIO2
  • dudlin 2
  • Dudlin-2
  • dudulin 2
  • dudulin-2
  • Dudulin-2,1010001D01Rik
  • EC 1.16.1.-
  • hpHyde
  • hTSAP6
  • metalloreductase STEAP3
  • pHyde
  • six transmembrane prostate protein 3
  • Six-transmembrane epithelial antigen of prostate 3
  • STEAP family member 3
  • STEAP3
  • STMP3
  • TSAP6
  • TSAP6STMP3
  • tumor suppressor pHyde
  • Tumor suppressor-activated pathway protein 6

Background

Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NAD(+) as acceptor (By similarity). May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol STEAP3
Entrez
Uniprot