STEAP3/TSAP6 Antibody - BSA Free

Western Blot: STEAP3/TSAP6 Antibody - BSA Free [NBP1-76824] - Western blot analysis of STEAP3/TSAP6 in HeLa cell lysate with STEAP3/TSAP6 antibody at (A) 1 and (B) 2 u/mL.

Immunocytochemistry/ Immunofluorescence: STEAP3/TSAP6 Antibody - BSA Free [NBP1-76824] - Immunofluorescence of STEAP3/TSAP6 in Mouse Liver cells with STEAP3/TSAP6 antibody at 20 ug/mL.

Immunohistochemistry: STEAP3/TSAP6 Antibody - BSA Free [NBP1-76824] - Immunohistochemistry of STEAP3/TSAP6 in mouse liver tissue with STEAP3/TSAP6 antibody at 2.5 ug/mL.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

STEAP3/TSAP6 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit STEAP3/TSAP6 Antibody - BSA Free (NBP1-76824) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human STEAP3. The immunogen is located within the first 50 amino acids of STEAP3. Amino Acid Squence: DSDSSLAKVPDEAPK
• Specificity: This STEAP3 antibody does not cross-react with other STEAP proteins.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: STEAP3
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/ml
  • Immunohistochemistry 2.5 ug/ml
  • Immunohistochemistry-Paraffin 2.5 ug/ml
  • Western Blot 1-2 ug/ml
• Theoretical MW: 51 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Control Peptide:

  STEAP3/TSAP6 Peptide (NBP1-76824PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for STEAP3/TSAP6 Antibody - BSA Free

• AHMIO2
• dudlin 2
• Dudlin-2
• dudulin 2
• dudulin-2
• Dudulin-2,1010001D01Rik
• EC 1.16.1.-
• hpHyde
• hTSAP6
• metalloreductase STEAP3
• pHyde
• six transmembrane prostate protein 3
• Six-transmembrane epithelial antigen of prostate 3
• STEAP family member 3
• STEAP3
• STMP3
• TSAP6
• TSAP6STMP3
• tumor suppressor pHyde
• Tumor suppressor-activated pathway protein 6

Background

The six-transmembrane epithelial antigen of prostate 3 (STEAP3) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP4), STEAP3 promotes both iron and copper reduction. STEAP3 is highly expressed in hematopoietic tissues and colocalizes with the transferrin endosome. Overexpression of STEAP3 stimulates iron reduction; mice lacking STEAP3 are deficient in erythroid ferrireductase activity, suggesting that STEAP3 is an endosomal ferrireductase required for transferrin-dependent iron uptake in erythroid cells. This STEAP3 antibody does not cross-react with other STEAP proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for STEAP3/TSAP6 Antibody (NBP1-76824)(1)

Publication using NBP1-76824

• Zhang W, Zhang M, Zhang J et al. The Six-Transmembrane Epithelial Antigen of the Prostate (STEAP) 3 Regulates the Myogenic Differentiation of Yunan Black Pig Muscle Satellite Cells (MuSCs) In Vitro via Iron Homeostasis and the PI3K/AKT Pathway. Cells 2025-05-13 [PMID: 40358178]

Bioinformatics

• Gene Symbol: STEAP3
• Uniprot:
  • AAH95421(Human)