Stathmin-2/STMN2 Antibody

Western Blot: Stathmin-2/STMN2 Antibody [NB100-1403] - (0.5ug/ml) staining of Mouse Foetal Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

• Reactivity: Mu, Hu, Rt, Bv, Ca
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

Stathmin-2/STMN2 Antibody Summary

• Description: The peptide used for immunization has been derived from the N-terminal domain.
• Immunogen: Peptide with sequence AKTAMAYKEK-C corresponding to N-Terminus according to NP_008960.2.
• Localization: Associated with punctate structures in the perinuclear cytoplasm, axons, and growth cones of developing neurons. STMN2 exists in both soluble and membrane-bound forms.
• Predicted Species: Human (100%), Rat (100%), Canine (100%), Bovine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: STMN2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:128000
  • Western Blot 0.3 - 1 ug/ml
• Application Notes: Western blot: Approx 20kDa band observed in Mouse Foetal Brain lysates (calculated MW of 20.8kDa according to NP_079561.1).
• Control:

  Human Brain Whole Tissue Lysate (Adult Whole Normal)
  Stathmin-2/STMN2 Overexpression Lysate

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Stathmin-2/STMN2 Antibody

• FLJ34868
• FLJ50995
• neuron-specific growth-associated protein
• Protein SCG10
• SCG10
• SCG10neuronal growth-associated protein (silencer element)
• SCGN10
• SCGN10stathmin-2
• Stathmin2
• Stathmin-2
• stathmin-like 2
• STMN2
• superior cervical ganglia, neural specific 10
• Superior cervical ganglion-10 protein

Background

STMN2 may play a role in neuronal differentiation, and in modulating membrane interaction with the cytoskeleton during neurite outgrowth.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Stathmin-2/STMN2 Antibody (NB100-1403)(1)

Publication using NB100-1403

• Bahn S, Mimmack M, Ryan M et al. Neuronal target genes of the neuron-restrictive silencer factor in neurospheresderived from fetuses with Down's syndrome: a gene expression study. Lancet 2002-01-26 [PMID: 11830198]

Bioinformatics

• Gene Symbol: STMN2
• Entrez:
  • 11075(Human)
  • 20257(Mouse)
• Uniprot:
  • NP_008960.(Human)