STAT2 Antibody

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Western Blot: STAT2 Antibody [NB100-56323] - Analysis of STAT2 in Jurkat cell lysate using this antibody at 3 ug/ml.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-56323
    • Availability
      Product Discontinued

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STAT2 Antibody Summary

Immunogen
This polyclonal antibody was developed against a synthetic peptide corresponding to amino acids 830-849 of human Stat2.
Specificity
In Jurkat, an approx. 113 kDa band is observed.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
STAT2
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot 3 - 5 ug/ml
Control
Jurkat Whole Cell Lysate
STAT2 Knockout HeLa Cell Lysate

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS containing 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein G purified

Alternate Names for STAT2 Antibody

  • interferon alpha induced transcriptional activator
  • ISGF-3
  • MGC59816
  • P113
  • signal transducer and activator of transcription 2
  • signal transducer and activator of transcription 2, 113kD
  • signal transducer and activator of transcription 2, 113kDa
  • STAT113
  • STAT2

Background

STATs (signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, STATs enter the nucleus to regulate transcription of many different genes. Among the seven STATs (STAT1, STAT2, STAT3, STAT4, STAT5a, STAT5b, and STAT6), STAT1, STAT3, STAT5A, and STAT5A have a wide activation profile. Human STAT2 cDNA codes for an 851 amino acid protein with a predicted molecular weight of 113 kDa. STAT2 associates with beta subunit of the type I IFN receptor in an interferon-dependent manner.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NB100-56323
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Applications: WB
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Product General Protocols

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Video Protocols

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for STAT2 Antibody (NB100-56323)

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Research Areas for STAT2 Antibody (NB100-56323)

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Blogs on STAT2.

Signal Transducer and Activator of Transcription STAT6: More than a Player in Allergic Inflammation
By Jamshed Arslan, Pharm. D., PhD. What is STAT6?The cellular pathway comprising tyrosine kinase Janus Kinase (JAK) and the transcription factor STAT connect extracellular signals from various cytokines, hormones an...  Read full blog post.

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Bioinformatics

Gene Symbol STAT2
Uniprot