STAT2 [p Tyr689] Antibody [Fluorescein] (IC2890F)

Images

 
Daudi human Burkitt's lymphoma cell line untreated (light orange filled histogram) or treated with Recombinant Human IFN‑ alpha A (Catalog # 11100-1) (dark orange filled histogram) was stained with Rabbit Anti-Human ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICFlow
Clonality
Polyclonal
Host
Rabbit
Conjugate
Fluorescein

Order Details

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Catalog# & Conjugate Size Price

STAT2 [p Tyr689] Antibody [Fluorescein] Summary

Immunogen
Phosphopeptide containing the human STAT2 Y689 site
Modification
p Tyr689
Specificity
Detects human STAT2 when phosphorylated at Y689 in Western blots.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
STAT2
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Intracellular Staining by Flow Cytometry 10 uL/10^6 cells
Publications
Read Publication using
IC2890F in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide
Purity
Antigen Affinity-purified

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for STAT2 [p Tyr689] Antibody [Fluorescein]

  • interferon alpha induced transcriptional activator
  • ISGF-3
  • MGC59816
  • P113
  • signal transducer and activator of transcription 2
  • signal transducer and activator of transcription 2, 113kD
  • signal transducer and activator of transcription 2, 113kDa
  • STAT113
  • STAT2

Background

STAT2 (Signal Transducer and Activator of Transcription #2) is a 113 kDa member of the STAT family of cytoplasmic transcription factors. STAT members generally mediate cytokine, growth factor and hormone receptor signal transduction. STAT2 is associated with Type I ( alpha - and beta -) Interferon signaling. All STATs contain an N‑terminal oligomerization domain, a DNA-binding domain, and an SH2-association region. STAT2 is phosphorylated at Y689 by receptor-associated Janus kinases (JAKs) leading to STAT2 dimerization and subsequent translocation to the nucleus to activate gene transcription.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for STAT2 Antibody (IC2890F)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Flow.


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Bioinformatics

Gene Symbol STAT2
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