Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
Immunogen affinity purified
Manufactured by SDIX's proprietary Genomic Antibody Technology. GAT FAQs.
Alternate Names for STAT1 Antibody
signal transducer and activator of transcription 1, 91kDa
signal transducer and activator of transcription-1
Stat-1 is a latent transcription factor that functions both as a signal transducer in the cytoplasm and an activator of transcription in the nucleus. Stat-1 is one of seven members of the Signal transducer and activators of transcription (Stats) family (1). Stat-1 is activated by a different number of ligands; IFN alpha, IFN gamma, EGF, PDGF and IL6 (2-3). Upon tyrosine phosphorylation, Stat-1 dimerize with Stat-2 and associates with ISGF3/IR9 to form the ISGF3 complex (4). This activation subsequently allows the complex to translocate to the nucleus & bind specific enhancer elements. Additional complexes can form upon IFN stimulation. (1)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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