STAT1 Products

Antibodies
STAT1 [p Tyr701] Antibody
STAT1 [p Tyr701] Antibody
AF2894
Species: Hu, Mu
Applications: WB, Simple Western, CyTOF-ready, Flow
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
STAT1 Antibody
STAT1 Antibody
NB100-56314
Species: Hu, Mu, Po, Ca, Pm
Applications: WB, IHC-P
Host: Rabbit Polyclonal
Lysates
STAT1 Overexpression Lysate
STAT1 Overexpression Lysate
NBP2-09841
Species: Hu
Applications: WB
STAT1 Overexpression Lysate
STAT1 Overexpression Lysate
NBL1-16524
Species: Hu
Applications: WB
Proteins
Recombinant Human STAT1 Prote ...
Recombinant Human STAT1 Protein
NBP1-48331
Species: Hu
Applications: PAGE
STAT1 Recombinant Protein Ant ...
STAT1 Recombinant Protein Antigen
NBP1-81578PEP
Species: Hu
Applications: AC
STAT1 Recombinant Protein Ant ...
STAT1 Recombinant Protein Antigen
NBP1-81579PEP
Species: Hu
Applications: AC

Description

STATs (signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, STATs enter the nucleus to regulate transcription of many different genes. Among the seven STATs (Stat1, Stat2, Stat3, Stat4, Stat5a, Stat5b, and Stat6), Stat1, Stat3, Stat5a, and Stat5b have a wide activation profile. STAT1 is activated by many different ligands including IFN family (IFN-a, IFN-b, IFN-g and IL-10), gp130 family (IL-6, IL-11, LIF, CNTF, and G-CSF), and receptor tyrosine kinases (EGF, PDGF, and CSF-1). STAT1 has two forms, the 91 kDa STAT1a and the 84 kDa STAT1b which are encoded by the same gene with splicing variant.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 6772
Alternate Names
  • signal transducer and activator of transcription-1
  • ISGF-3,91kD
  • DKFZp686B04100
  • signal transducer and activator of transcription 1, 91kDa

Research Areas for STAT1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Breast Cancer
Cancer
Phospho-Specific
Signal Transduction
Transcription Factors and Regulators

Bioinformatics Tool for STAT1

Discover related pathways, diseases and genes to STAT1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related STAT1 Blog Posts

Check out the latest blog posts on STAT1.
Signal Transducer and Activator of Transcription STAT6: More than a Player in Allergic Inflammation
By Jamshed Arslan, Pharm. D., PhD. What is STAT6?The cellular pathway comprising tyrosine kinase Janus Kinase (JAK) and the transcription factor STAT connect extracellular signals from various cytokines, hormones an...    Read more.
Using a STAT3 antibody in chromatin immunoprecipitation (ChIP)
Signal transducer and activator of transcription 3 (STAT3) is an important oncogenic transcriptional factor that mediates tumor induced immune suppression.  Specifically, STAT3 transmits signals from cytokines and growth factor receptors in the pla...    Read more.
Read more STAT1 related blogs.