Stargazin Antibody

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Western Blot: Stargazin Antibody [NB100-61089]

Product Details

Summary
Reactivity Rt, MuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Stargazin Antibody Summary

Immunogen
Peptide corresponding to amino acid residues from the C-terminal region of rat stargazin, conjugated to keyhole limpet hemocyanin (KLH).
Specificity
Specific for the ~36k stargazin protein. Immunolabeling of the stargazin band is blocked by preadsorption with the peptide used as antigen.
Predicted Species
Mouse (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CACNG2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000
Theoretical MW
36 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

It is anticipated that the antibody will also work with mouse tissue based on the fact that this species has 100% homology with the amino acid sequence used as antigen.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol
Preservative
No Preservative
Purity
Immunogen affinity purified

Alternate Names for Stargazin Antibody

  • calcium channel, voltage-dependent, gamma subunit 2
  • FLJ41437
  • MGC138502
  • MGC138504
  • Neuronal voltage-gated calcium channel gamma-2 subunit
  • stargazin
  • voltage-dependent calcium channel gamma-2 subunit

Background

Stargazin is a member of the transmembrane AMPAR regulatory proteins (TARP) family and is involved in glutamate receptor trafficking. It has been recently demonstrated (Tomita et al., 2005; Priel et al., 2005) that the interaction between stargazin and AMPA receptors is critical for the correct localization of the receptors at the synapse. Phosphorylation of the stargazin protein at Thr 321 by Protein Kinase A regulates its interaction with PSD-95 and synaptic targeting of AMPA receptors (Choi et al., 2002). Stargazin mutant mice are utilized as a model for absence epilepsy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for Stargazin Antibody (NB100-61089). (Showing 1 - 1 of 1 FAQ).

  1. Could you please provide the immunogen sequence for catalog number NB100-61089 at your earliest convenience? If the exact sequence is not available, could you please tell me a broader range of amino acids or the region of the peptide from which it is derived?
    • The sequence is proprietary but I can tell you that it was taken from the last 50 amino acids of the rat sequence.

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CACNG2
Entrez
Uniprot