Stargazin Antibody - Azide Free

Western Blot: Stargazin Antibody [NB100-61089]

• Reactivity: Rt, Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide Free

Stargazin Antibody - Azide Free Summary

• Description: Novus Biologicals Rabbit Stargazin Antibody - Azide Free (NB100-61089) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH. Accession # O88602
• Specificity: Specific for endogenous levels of the ~36kDa stargazin protein. Immunolabeling of the stargazin band is blocked by preadsorption with the peptide used as antigen.
• Predicted Species: Mouse (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CACNG2
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:1000
• Theoretical MW: 36 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: 10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol
• Preservative: No Preservative
• Purity: Antigen Affinity-purified

Alternate Names for Stargazin Antibody - Azide Free

• calcium channel, voltage-dependent, gamma subunit 2
• FLJ41437
• MGC138502
• MGC138504
• Neuronal voltage-gated calcium channel gamma-2 subunit
• stargazin
• voltage-dependent calcium channel gamma-2 subunit

Background

Stargazin is a member of the transmembrane AMPAR regulatory proteins (TARP) family and is involved in glutamate receptor trafficking. It has been recently demonstrated (Tomita et al., 2005; Priel et al., 2005) that the interaction between stargazin and AMPA receptors is critical for the correct localization of the receptors at the synapse. Phosphorylation of the stargazin protein at Thr 321 by Protein Kinase A regulates its interaction with PSD-95 and synaptic targeting of AMPA receptors (Choi et al., 2002). Stargazin mutant mice are utilized as a model for absence epilepsy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

FAQs for Stargazin Antibody (NB100-61089). (Showing 1 - 1 of 1 FAQ).

1. Could you please provide the immunogen sequence for catalog number NB100-61089 at your earliest convenience? If the exact sequence is not available, could you please tell me a broader range of amino acids or the region of the peptide from which it is derived?
   • The sequence is proprietary but I can tell you that it was taken from the last 50 amino acids of the rat sequence.

Bioinformatics

• Gene Symbol: CACNG2
• Entrez:
  • 12300(Mouse)
  • 84347(Rat)
• Uniprot:
  • Q71RJ2(Rat)