SREBP2 Antibody


Immunoprecipitation: SREBP2 Antibody [NBP1-71880] - Samples: Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit more

Product Details

Reactivity Hu, Bovine, Canine, Chicken, Equine, Guinea Pig, Primate, Porcine, Rat, MonkeySpecies Glossary
Applications WB, IP
1 mg/ml

Order Details

SREBP2 Antibody Summary

The immunogen for this product maps to a region between residue 300 and 350 of human Sterol Regulatory Element Binding Transcription Factor 2 using the numbering given in entry NP_004590.2 (GeneID 6721).
Predicted Species
Rat (100%), Porcine (100%), Canine (100%), Monkey (100%), Primate (100%), Equine (100%), Chicken (100%), Guinea Pig (100%), Bovine (100%). Backed by our 100% Guarantee.
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at 4C. Do not freeze.
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
0.09% Sodium Azide
1 mg/ml
Immunogen affinity purified


  • Western Blot 1:1000-1:5000
  • Immunoprecipitation 2- 10 ug/mg lysate
Read Publication using
NBP1-71880 in the following applications:

  • WB
    1 publication

Reactivity Notes

Based on 100% sequence identity, this antibody is predicted to react with Panda, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, White-tufted ear marmoset, European domestic ferret, Chinese hamster, Naked mole rat and Little brown bat.

Alternate Names for SREBP2 Antibody

  • bHLhd2
  • bHLHd2sterol regulatory element-binding protein 2
  • Class D basic helix-loop-helix protein 2
  • SREBF2
  • SREBP2
  • sterol regulatory element binding transcription factor 2
  • Sterol regulatory element-binding transcription factor 2


This gene encodes a ubiquitously expressed transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Species: Hu, Bovine, Canine, Chicken, Equine, Guinea Pig, Primate, Porcine, Rat, Monkey
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Publications for SREBP2 Antibody (NBP1-71880)(1)

We have publications tested in 1 confirmed species: ZebraFish.

We have publications tested in 1 application: WB.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

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Secondary Antibodies


Isotype Controls

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Bioinformatics Tool for SREBP2 Antibody (NBP1-71880)

Discover related pathways, diseases and genes to SREBP2 Antibody (NBP1-71880). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Blogs on SREBP2.

SREBP2 - regulating cholesterol homeostasis and lipid metabolism
Sterol regulatory element-binding proteins (SREBP) are important transcription factors regulating the synthesis and uptake of lipids including cholesterol. This essential role in lipid metabolism makes investigations into the functions SREBPs im...  Read full blog post.

SREBP: Gatekeeper of Cholesterol Homeostasis
SREBP1 (sterol-regulatory-element-binding protein 2) is a basic-helix-loop-helix-leucine zipper (bHLH-ZIP) transcription factor. It regulates sterol and cholesterol homeostasis by controlling enzymes involved in cholesterol synthesis and uptake, e.g....  Read full blog post.

SREBPs: Global Regulator of Lipid Metabolism
Sterol regulatory element binding proteins (SREBPs) are indirectly required for cholesterol biosynthesis and for uptake and fatty acid biosynthesis. There are three known SREBP isoforms, SREBP1a, 1c and SREBP2; these have different roles in lipid synt...  Read full blog post.

SREBP2: From Cholesterol Homeostasis to Cancer Invasion
Sterol-regulatory-element-binding protein 2 (SREBP2) is a transcription factor that regulates cholesterol homeostasis by controlling enzymes involved in cholesterol synthesis and uptake, e.g. HMG-CoA. Along with another transcription factor LXR, SREBP...  Read full blog post.

ABCA1 Expression is Down-Regulated by SREBP microRNA
The ABCA1 (ATP-binding cassette transporter-A1) gene encodes a transmembrane protein, which plays a major role in phospholipid homeostasis by regulating cholesterol efflux from the cell. ABCA1 antibody studies have shown ABCA1 expression is up/down re...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol SREBF2

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