SREBP2 Antibody

Product Discontinued

SREBP2 Antibody Summary

• Immunogen: Recombinant fragment corresponding to a region within amino acids 604 and 821 of SREBF2 (Uniprot ID#Q12772)
• Localization: Endoplasmic reticulum membrane, Multi-pass membrane protein, Golgi apparatus membrane, Multi-pass membrane protein, Cytoplasmic vesicle, COPII-coated vesicle membrane, Multi-pass membrane protein, Processed sterol regulatory element-binding protein 2:
• Predicted Species: Mouse (94%), Rat (97%), Bovine (97%). Backed by our 100% Guarantee.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SREBF2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:10-1:2000
  • Western Blot 1:500-1:3000
• Theoretical MW: 124 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Not yet tested in any other species.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris (pH 7.0), 0.1M Glycine and 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Immunogen affinity purified

Alternate Names for SREBP2 Antibody

• bHLhd2
• bHLHd2sterol regulatory element-binding protein 2
• Class D basic helix-loop-helix protein 2
• SREBF2
• SREBP2
• SREBP2SREBP-2
• sterol regulatory element binding transcription factor 2
• Sterol regulatory element-binding transcription factor 2

Background

This gene encodes a ubiquitously expressed transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SREBF2
• Entrez:
  • 6721(Human)
• Uniprot:
  • Q12772(Human)