SP8 Antibody

Product Discontinued

SP8 Antibody Summary

• Immunogen: Synthetic peptide from mouse Sp8.
• Specificity: Sp8, a zinc finger transcription factor. By Western Blot the antibody recognizes a band at ~50 kDa on mouse brain lysate.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SP8
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 05-2 ug/ml
• Application Notes: Western Blot:Suggested dilution works well on mouse brain lysate.
• Theoretical MW: 50 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Relevant Entrez Gene Numbers: NM_182700.2;NM_198956.1

Alternate Names for SP8 Antibody

• transcription factor Sp8
• BTD
• Sp8 transcription factor

Background

SP8 is a gene that codes for a protein with four isoforms, measuring 490, 448, 434, and 508 amino acids in length with weights of approximately 49, 45, 44, and 51 kDa respectively. The protein encoded by SP8 functions as a transcription factor that plays a role in limb development by regulating FGF8 expression in the apical ectodermal ridge. Current studies are being done on diseases and disorders related to this gene including bipolar disorder, brain injuries, and papilloma. SP8 has also been shown to have interactions with HYL, ZNF273, ZNF519, CELA3B, and INTS7.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SP8
• Uniprot:
  • Q8IXZ3(Human)