SP8 Products

Description

SP8 is a gene that codes for a protein with four isoforms, measuring 490, 448, 434, and 508 amino acids in length with weights of approximately 49, 45, 44, and 51 kDa respectively. The protein encoded by SP8 functions as a transcription factor that plays a role in limb development by regulating FGF8 expression in the apical ectodermal ridge. Current studies are being done on diseases and disorders related to this gene including bipolar disorder, brain injuries, and papilloma. SP8 has also been shown to have interactions with HYL, ZNF273, ZNF519, CELA3B, and INTS7.

Bioinformatics

Entrez	221833 Human
Product By Gene ID	221833
Alternate Names	transcription factor Sp8 BTD Sp8 transcription factor

Diseases related to SP8

Discover more about diseases related to SP8.

Nervousness
Malignant Neoplasms
Limb Deformities, Congenital
Immunologic Deficiency Syndromes
Hemorrhage
Neoplasms
Hiv Infections
Acquired Immunodeficiency Syndrome
Neoplasm Metastasis
Melanoma
Ectrodactyly
Pain
Brain Injuries
Cleft Palate
Liver Neoplasms
Uveal Melanoma
Primary Dysmenorrhea
Cerebrovascular Accident
Dental Plaque
Cleft Lip

Pathways for SP8

View related products by pathway and learn more about each of the pathways below.

Limb Development
Cell Adhesion
Neurogenesis
Localization
Regionalization
Pathogenesis
Olfactory Bulb Interneuron Development
Cell Proliferation
Head Development
Cell Development
Brain Development
Immune Response
Ossification
Dna Replication
Menstruation
Limb Morphogenesis
Cell Death
Neuropore Closure
Cell Growth
Cognition

PTMs for SP8

Learn more about PTMs related to SP8.

Cleavage
Methylation

Bioinformatics Tool for SP8

Discover related pathways, diseases and genes to SP8. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.