Somatostatin R3/SSTR3 Antibody

Product Discontinued

Somatostatin R3/SSTR3 Antibody Summary

• Immunogen: Synthetic 16 amino acid peptide from C-terminus of human SSTR3.
• Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Monkey (94%), Primate (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SSTR3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 10-15 ug/ml
  • Immunohistochemistry-Paraffin 10-15 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (94%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Somatostatin R3/SSTR3 Antibody

• Somatostatin R3
• somatostatin receptor 3
• SomatostatinR3
• SS-3-R
• SS3-R
• SSR-28
• SST3
• SSTR3

Background

Somatostatin is a tetradecapeptide that is widely distributed in the body. It acts on multiple organs in the body and also functions as a neuropeptide affecting electrical activity of neurons. Somatostatin acts to regulate numerous physiological processes by binding to and activating specific receptors in target tissues. There are five somatostatin receptor subtypes termed SSTR 1 to 5. They are G protein coupled receptors characterized by seven transmembrane helices with an extracellular amino terminal domain and an intracellular carboxy terminus. These receptors are activated by somatostatin secreted by nerve and endocrine cells and function in the regulation of numerous physiological processes such as the secretion of insulin, glucagon and growth hormone. The SSTRs also play a role in cell growth induced by neuronal excitation in both the central and peripheral nervous system. Somatostatin receptors have been implicated in numerous diseases ranging from Alzheimer's to cancers of the gastrointestinal tract, breast, prostate, and pituitary.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SSTR3