SNW1 Antibody

Images

 
Western Blot: SNW1 Antibody [NB100-2367] - Detection of Human and Mouse NCOA62 on HeLa whole cell lysate using NB100-2367. NCOA62 was also immunoprecipitated by rabbit anti-NCOA62 antibody NB100-2368.
Immunohistochemistry: SNW1 Antibody [NB100-2367] - Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti- NCOA62 used at a dilution of 1:1,000 (1ug/ml). Detection: DAB
Immunohistochemistry-Paraffin: SNW1 Antibody [NB100-2367] - FFPE section of human thyroid carcinoma. Affinity purified rabbit anti-NCOA62 used at a dilution of 1:250.
Immunohistochemistry-Paraffin: SNW1 Antibody [NB100-2367] - FFPE section of mouse squamous cell carcinoma. Affinity purified rabbit anti-NCOA62 used at a dilution of 1:250.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC, IHC-P, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml
 

Independent Antibodies

 

Biological Strategies

     

Order Details

SNW1 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 450 and 500 of human Nuclear Receptor Coactivator, 62 kD (SKIIP, SKI Interacting Protein) using the numbering given in entry NP_036377.1 (GeneID 22938).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SNW1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunohistochemistry 1:250
  • Immunohistochemistry-Paraffin 1:250
  • Immunoprecipitation 2-5 ug/mg lysate
Theoretical MW
61 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for SNW1 Antibody

  • Bx42
  • homolog of Drosophila BX42
  • MGC119379
  • NCoA-62
  • Nuclear protein SkiP
  • Nuclear receptor coactivator NCoA-62
  • nuclear receptor coactivator, 62-kD
  • Prp45
  • PRPF45
  • SKI interacting protein
  • Ski-interacting protein
  • SKIPSKIIP
  • SNW domain containing 1
  • SNW domain-containing protein 1

Background

This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SNW1
Entrez
Uniprot