Western Blot: SMG7 Antibody [NBP1-22967] - Western Blot and Immunoprecipitation: by Western Blot : Whole cell lysate from HeLa, 293T and mouse NIH3T3 cells. SMG7 was also immunoprecipitated byanother rabbit anti-SMG7 ...read more
The immunogen recognized by this antibody maps to a region between residue 1087 and 1137 of human suppressor with morphogenetic effect on genitalia protein 7 (ever shorter telomeres 1C) using the numbering given in entry NP_775179.1 (GeneID 9887).
Immunogen affinity purified
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SMG7 plays a role in the dephosphorylation of UPF1, an RNA-dependent ATPase and helicase critical to nonsense-mediated mRNA decay (NMD). It is a homolog of the C. elegans NMD factor Smg7 (suppressor with morphogenetic effect on genitalia protein 7). SMG7 functions as an adaptor to target protein phosphatase 2A to UPF1 for dephosphorylation of UPF1.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.