SMG7 Antibody

Images

 
Western Blot: SMG7 Antibody [NBP1-22967] - Western Blot and Immunoprecipitation: by Western Blot : Whole cell lysate from HeLa, 293T and mouse NIH3T3 cells. SMG7 was also immunoprecipitated byanother rabbit anti-SMG7 ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.2 mg/ml
 

Independent Antibodies

 

Biological Strategies

     

Order Details

SMG7 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 1087 and 1137 of human suppressor with morphogenetic effect on genitalia protein 7 (ever shorter telomeres 1C) using the numbering given in entry NP_775179.1 (GeneID 9887).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SMG7
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation 5-15 ug/mg lysate
Publications
Read Publications using
NBP1-22967 in the following applications:

  • WB
    2 publications

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for SMG7 Antibody

  • breast cancer-associated antigen SGA-56M
  • C1orf16
  • chromosome 1 open reading frame 16
  • EST1 telomerase component homolog C
  • EST1CKIAA0250SGA56M
  • EST1-like protein C
  • ever shorter telomeres 1C
  • FLJ23717
  • hSMG-7
  • protein SMG7
  • SMG-7 homolog
  • Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
  • SMG-7

Background

SMG7 plays a role in the dephosphorylation of UPF1, an RNA-dependent ATPase and helicase critical to nonsense-mediated mRNA decay (NMD). It is a homolog of the C. elegans NMD factor Smg7 (suppressor with morphogenetic effect on genitalia protein 7). SMG7 functions as an adaptor to target protein phosphatase 2A to UPF1 for dephosphorylation of UPF1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for SMG7 Antibody (NBP1-22967)(2)

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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SMG7 NBP1-22967

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Diseases for SMG7 Antibody (NBP1-22967)

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Bioinformatics

Gene Symbol SMG7
Entrez
Uniprot