Western Blot: SIRT7 Antibody [NB100-56364] - Immunoblots reveal the levels of sirtuins (SIRT4-7) in the OSCC cell lines HSC-3, UM-SCC-1, and UM-SCC-17B and in normal human oral keratinocytes (K). B-Actin served as ...read more
Western Blot: SIRT7 Antibody [NB100-56364] - Analysis of SIRT7 in A) human liver and B) PBMC lysate using this antibody at 1 ug/ml.
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.05% Sodium Azide
Protein G purified
Alternate Names for SIRT7 Antibody
silent mating type information regulation 2, S.cerevisiae, homolog 7
SIR2L7NAD-dependent deacetylase sirtuin-7
SIR2-like protein 7
sir2-related protein type 7
sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae)
sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 7
sirtuin type 7
SIRT7 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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