SIPA1 Antibody [PerCP]

• Reactivity: Hu, Mu
• Applications: WB, ELISA, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: PerCP

SIPA1 Antibody [PerCP] Summary

• Immunogen: SIPA1 antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human SIPA1. The immunogen is located within amino acids 40 - 90 of SIPA1. Amino Acid Squence: DAGEARPPTPASPRARAHS
• Specificity: At least three isoforms of SIPA1 are known to exist; this antibody will recognize all three isoforms. This antibody is specific for SIPA1 and will not recognize the other SIPA1 family of proteins.
• Predicted Species: Mouse (95%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SIPA1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Peptide affinity purified

Alternate Names for SIPA1 Antibody [PerCP]

• GTPase-activating protein Spa-1
• MGC102688
• MGC17037
• p130 SPA-1
• signal-induced proliferation-associated 1
• signal-induced proliferation-associated protein 1
• sipa-1
• SPA1signal-induced proliferation-associated gene 1

Background

The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SIPA1