SH2D1B [p Tyr127] Antibody

Product Discontinued

SH2D1B [p Tyr127] Antibody Summary

• Immunogen: Peptide with sequence C-NSNSDpYVDVLP corresponding to internal region according to NP_444512.2.
• Epitope: C-NSNSDpYVDVLP
• Modification: p Tyr127
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: SH2D1B
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:128000
  • Western Blot 0.3 - 1 ug/ml
• Application Notes: WB: Approx. 14 kDa band observed in A431 lysates (calculated MW of 16.6 kDa band according to NP_002643.1).

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for SH2D1B [p Tyr127] Antibody

• EAT2EAT-2
• EWS/FLI1-activated transcript 2
• SH2 domain containing 1B
• SH2 domain-containing molecule EAT2
• SH2 domain-containing protein 1B

Background

By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SH2D1B
• Entrez:
  • 117157(Human)
• Uniprot:
  • NP_444512.2(Human)