SGSM2 Antibody

Immunocytochemistry/Immunofluorescence: SGSM2 Antibody [NBP1-93637] - Staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.

Immunohistochemistry-Paraffin: SGSM2 Antibody [NBP1-93637] - Staining of human cerebral cortex shows cytoplasmic positivity in neuronal and glia cells.

• Reactivity: Hu
• Applications: WB, ICC/IF, IHC, IHC-P
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

SGSM2 Antibody Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: SGIQSSLDEGQSVGFEEEDGGGEEGSSGPGPAAHTLREPQDPSQEKPQAGELEAGEELAAVCAAAYTIELLDTVALNLHRIDKDVQRCDRNYWY
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SGSM2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
  • Western Blot 0.04-0.4 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100. Use in Western blot reported in reported in scientific literature (PMID: 30744493).
• Control Peptide:

  SGSM2 Protein (NBP1-93637PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (80%), Rat (80%)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for SGSM2 Antibody

• KIAA0397
• RUN and TBC1 domain containing 1
• RUN and TBC1 domain-containing protein 1
• RUTBC1
• small G protein signaling modulator 2 protein
• small G protein signaling modulator 2

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SGSM2 Antibody (NBP1-93637)(1)

Publication using NBP1-93637

• Lin JH, Lee WJ, Wu HC et al. Small G protein signalling modulator 2 (SGSM2) is involved in oestrogen receptor-positive breast cancer metastasis through enhancement of migratory cell adhesion via interaction with E-cadherin Cell Adh Migr 2019-02-11 [PMID: 30744493] (IHC, WB, Human)

Bioinformatics

• Gene Symbol: SGSM2