SETMAR Antibody [DyLight 405]

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: DyLight 405

SETMAR Antibody [DyLight 405] Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 1 and 50 of human SET Domain and Mariner Transposase Fusion Gene-Containing Protein using the numbering given in entry BAD96454.1 (GeneID 6419).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SETMAR
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for SETMAR Antibody [DyLight 405]

• EC 2.1.1.43
• histone-lysine N-methyltransferase SETMAR
• hsMar1
• Metnase
• SET domain and mariner transposase fusion gene
• SET domain and mariner transposase fusion gene-containing protein

Background

Histone methyltransferase that methylates 'Lys-4' and 'Lys-36' of histone H3, 2 specific tags for epigenetic transcriptional activation. Specifically mediates dimethylation of H3 'Lys-36'. Has sequence-specific DNA-binding activity and recognizes the 19-mer core of the 5'-terminal inverted repeats (TIRs) of the Hsmar1 element. Has DNA nicking activity. Has in vivo end joining activity and may mediate genomic integration of foreign DNA

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SETMAR