SET1B Antibody

Images

 
Immunohistochemistry: SET1B Antibody [NBP1-28684] - Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-hSET1B used at a dilution of 1:1,000 (1ug/ml). Detection: DAB
Immunohistochemistry-Paraffin: SET1B Antibody [NBP1-28684] - FFPE section of human breast carcinoma. Antibody used at a dilution of 1:250. Detection: DAB staining using Immunohistochemistry Accessory Kit.
Immunohistochemistry-Paraffin: SET1B Antibody [NBP1-28684] - FFPE section of human ovarian carcinoma. Antibody used at a dilution of 1:250. Detection: DAB staining using Immunohistochemistry Accessory Kit.
Immunoprecipitation: SET1B Antibody [NBP1-28684] - Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-SET1B antibody NBP1-28684 used for IP at 10 ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC-P, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

SET1B Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 350 and 400 of human SET domain containing 1B using the numbering given in entry NP_055863.1 (GeneID 23067).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SETD1B
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1:500-1:2000
  • Immunoprecipitation 10 ug/mg
Application Notes
Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for SET1B Antibody

  • EC 2.1.1
  • FLJ20803
  • histone-lysine N-methyltransferase SETD1B
  • hSET1B
  • KIAA1076EC 2.1.1.43
  • KMT2GSET1B
  • Lysine N-methyltransferase 2G
  • SET domain containing 1B
  • SET domain-containing protein 1B
  • Set1B

Background

hSET1B is a histone methyltransferase that associates in a complex with the non-catalytic subunits CFP1, Rbbp5, Ash2, Wdr5, and Wdr82. These five non-catalytic subunits are also part of the Set1A complex. The SET1B complex has been shown to catalyze the tri-methylation of 'Lys-4' on histone H3. SET1B has been shown to localize to sites independent of SET1A complexes indicating non-redundant functions between SET1B and SET1A complexes. hSET1B include SET domain-containing protein 1B, lysine N-methyltransferase 2G, SETD1B, KMT2G, SET1B, and KIAA1076.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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SET1B NBP1-28684

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Bioinformatics

Gene Symbol SETD1B
Entrez
Uniprot