SET Antibody

Western Blot: SET Antibody [NBP1-26647] - Whole cell lysate from HeLa and 293T cells. SET was also immunoprecipitated by rabbit anti-SET antibody NBP1-26646.

Immunohistochemistry-Paraffin: SET Antibody [NBP1-26647] - Staining of human prostate carcinoma

• Reactivity: Hu
• Applications: WB, IHC, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

SET Antibody Summary

• Description: Novus Biologicals Rabbit SET Antibody (NBP1-26647) is a polyclonal antibody validated for use in IHC, WB and IP. Anti-SET Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: The immunogen recognized by this antibody maps to a region between residue 175 and 225 of human SET nuclear oncogene using the numbering given in entry NP_001116293.1 (GeneID 6418).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SET
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:200
  • Immunoprecipitation 3 -5 ug/mg lysate
  • Western Blot 1:2000 -1:10000
• Application Notes: Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: TBS and 0.1% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for SET Antibody

• 2PP2A
• HLA-DR-associated protein II
• I2PP2A
• I-2PP2A
• IGAAD
• Inhibitor of granzyme A-activated DNase
• inhibitor-2 of protein phosphatase-2A
• IPP2A2
• PHAPIITAF-I
• Phosphatase 2A inhibitor I2PP2A
• protein phosphatase type 2A inhibitor
• protein SET
• SET nuclear oncogene
• SET translocation (myeloid leukemia-associated)
• TAF-IBETA
• Template-activating factor I
• Template-Activating Factor-I, chromatin remodelling factor

Background

SET is a multi-functional protein involved in apoptosis, transcription, nucleosome assembly, and histone binding. SET was identified as part of a chromosomal rearrangement with NUP214/CAN in acute undifferentiated leukemia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SET Antibody (NBP1-26647)(1)

Publication using NBP1-26647

• Dikovskaya D, Khoudoli G, Newton IP et al. The adenomatous polyposis coli protein contributes to normal compaction of mitotic chromatin. PLoS One 2012-01-01 [PMID: 22719865]

Bioinformatics

• Gene Symbol: SET
• Entrez:
  • 6418(Human)
• Uniprot:
  • NP_001116293.1(Human)