Serum Amyloid A4 Antibody [Unconjugated]

• Reactivity: Mu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: LYOPH

Serum Amyloid A4 Antibody [Unconjugated] Summary

• Immunogen: E. coli-derived recombinant mouse Serum Amyloid A4
  Asp19-Phe130
  Accession # P31532
• Specificity: Detects mouse Serum Amyloid A4 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 15% cross‑reactivity with recombinant human Serum Amyloid A4 is observed and less than 1% cross-reactivity with recombinant mouse Serum Amyloid A1 is observed.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: SAA4
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 25 ug/mL
  • Western Blot 0.1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Serum Amyloid A4 Antibody [Unconjugated]

• C-SAA
• C-SAACSAAConstitutively expressed serum amyloid A protein
• SAA4
• SAA5
• serum amyloid A-4 protein
• Serum Amyloid A4
• serum amyloid A4, constitutive

Background

Mouse serum amyloid A protein-4 (SAA4; also SAA5) is a 14 kDa member of the SAA family of proteins. It is a constitutively produced apolipoprotein component of HDL that may mediate HDL-VLDL interactions. Mature mouse SAA4 is 112 amino acids (aa) in length. There are no notable motifs. Although human SAA4 is glycosylated, mouse SAA4 is not. Human SAA4 also shows truncation of its Lys-Lys-Tyr C-terminus. The mouse C-terminus is distantly related with a Glu-Lys-Phe tripeptide, but it is unknown if it is proteolytically processed. Over aa 19‑130, mouse SAA4 shares 57% and 85% aa identity with mature human and rat SAA4, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SAA4
• Uniprot:
  • P31532()