Serum Amyloid A4 Antibody (398104) [Alexa Fluor® 594]

• Reactivity: Mu
• Applications: IHC
• Clone: 398104
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 594

Serum Amyloid A4 Antibody (398104) [Alexa Fluor® 594] Summary

• Immunogen: E.coli-derived recombinant mouse Serum Amyloid A4
  Asp19-Phe130
  Accession # P31532
• Specificity: Detects mouse Serum Amyloid A4 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) Serum Amyloid A1, rhSerum Amyloid A4, or recombinant mouse Serum Amyloid A1 is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Serum Amyloid A4 Antibody (398104) [Alexa Fluor® 594]

• C-SAA
• C-SAACSAAConstitutively expressed serum amyloid A protein
• SAA4
• SAA5
• serum amyloid A-4 protein
• Serum Amyloid A4
• serum amyloid A4, constitutive

Background

Mouse Serum Amyloid A4 (SAA4; also SAA5) is a 14 kDa member of the SAA family of proteins.  It is a constitutively produced apolipoprotein component of HDL that may mediate HDL-VLDL interactions.  Mature mouse SAA4 is 112 amino acids (aa) in length.  Although human SAA4 is glycosylated, mouse SAA4 is not.  Human SAA4 also shows truncation of its Lys-Lys-Tyr C-terminus. The mouse C-terminus is distantly related with a Glu-Lys-Phe tripeptide, but it is unknown if it is proteolytically processed. Over aa 19-130, mouse SAA4 shares 57% and 85% aa identity with mature human and rat SAA4, respectively.   

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.