Serpin E1/PAI-1 Antibody (MA-33H1F7)


There are currently no images for Serpin E1/PAI-1 Antibody (NBP1-51518).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Reactivity Hu, Rt, RbSpecies Glossary
Applications WB, IA
0.1 mg/ml

Order Details

Serpin E1/PAI-1 Antibody (MA-33H1F7) Summary

The immunogen for this antibody is proprietary informatiom.
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Store at 4C. Do not freeze.
0.2 um filtered antibody solution in PBS, containing 0.1% bovine serum albumin.
No Preservative
0.1 mg/ml
Protein A or G purified


Application Notes
This product works in Immunoassay, and Western Blot. Although not tested this antibody may work in Functional Studies.

Reactivity Notes

Human, Rat, Rabbit

Alternate Names for Serpin E1/PAI-1 Antibody (MA-33H1F7)

  • Endothelial plasminogen activator inhibitor
  • Nexin
  • PAI1
  • PAI-1
  • PAI1PAI-1
  • PAISerpin E1
  • PLANH1
  • PLANH1plasminogen activator inhibitor 1
  • serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogenactivator inhibitor type 1), member 1
  • serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitortype 1), member 1


Plasminogen activator inhibitor type-1 (PAI-1), a member of the serine protease inhibitor (serpin) superfamily is an important protein in the regulation of fibrinolysis. PAI-1 is unique among the serpins because of its functional and conformational flexibility. PAI-1 is the most important physiological inhibitor of both tissue-type plasminogen activator (t-PA) and urokinase-type plasminogen activator (u-PA). Increased PAI-1 levels are associated with thrombotic events and is an established risk factor for cardiovascular diseases. The active conformation PAI-1 inhibits its target proteinases by the formation of a stable, inactive complex. Although PAI-1 is synthesized as an active molecule, it converts spontaneously to an inactive, latent form that can be partially reactivated by denaturing agents. In addition, a third conformation reacting as a non-inhibitory substrate towards various target proteinases has been identified. The epitope of monoclonal antibody MA-33H1F7 is predominantly composed of three residues (Lys154/Glu130/Arg131), positioned virtually linearly in the three-dimensional structure. The epitope of the antibody does not cover the complete alpha-helix F and turn connecting alpha-helix F and beta-strand s3A, but is restricted to the hinge region between alpha-helix F and the main part of the PAI-1 molecule. The monoclonal antibody MA-33H1F7 is a 'switching' antibody, capable of inducing a non-inhibitory substrate form of PAI-1. The antibody cross reacts with rat, mouse and rabbit PAI-1.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu, Ba
Applications: WB, ELISA
Species: Hu
Applications: WB, IHC, IHC-P
Species: Hu
Applications: WB, ELISA, PA
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, Flow, IHC, IHC-P
Species: Hu
Applications: WB, IHC, IHC-P
Species: Hu
Applications: WB, ELISA, ICC/IF, S-ELISA
Species: Hu
Applications: PAGE
Species: Hu, Mu
Applications: WB, Flow, IHC, IHC-P
Species: Hu, Rt, Rb
Applications: WB, IA

Publications for Serpin E1/PAI-1 Antibody (NBP1-51518) (0)

There are no publications for Serpin E1/PAI-1 Antibody (NBP1-51518).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Serpin E1/PAI-1 Antibody (NBP1-51518) (0)

There are no reviews for Serpin E1/PAI-1 Antibody (NBP1-51518). By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Serpin E1/PAI-1 Antibody (NBP1-51518) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies


Isotype Controls

Additional Serpin E1/PAI-1 Antibody (MA-33H1F7) Products

Related Products by Gene

Bioinformatics Tool for Serpin E1/PAI-1 Antibody (NBP1-51518)

Discover related pathways, diseases and genes to Serpin E1/PAI-1 Antibody (NBP1-51518). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Serpin E1/PAI-1 Antibody (NBP1-51518)

Discover more about diseases related to Serpin E1/PAI-1 Antibody (NBP1-51518).

Pathways for Serpin E1/PAI-1 Antibody (NBP1-51518)

View related products by pathway.

PTMs for Serpin E1/PAI-1 Antibody (NBP1-51518)

Learn more about PTMs related to Serpin E1/PAI-1 Antibody (NBP1-51518).

Research Areas for Serpin E1/PAI-1 Antibody (NBP1-51518)

Find related products by research area.

Blogs on Serpin E1/PAI-1

There are no specific blogs for Serpin E1/PAI-1, but you can read our latest blog posts.

Contact Information

Product PDFs


Gene Symbol SERPINE1

Customer Resources

Novus Review - Submit your review and earn rewards points which can be used for merchandise & discounts.
Risk Free Testing - Test on a species/application not listed above to receive a full credit towards a future purchase.

Novus' Quality Guarantee - Novus guarantees that every product we sell will work in the application and species listed on our website and datasheets.

Submit your question on NBP1-51518 below.
During business hours, we will respond to your email within 24 hours. For any questions submitted on the weekend, a response will be received on Monday.
For immediate assistance during business hours M- F (excluding major holidays), please contact us.
Ask a Scientist - We have a lab full of white coats just waiting for your scientific questions and concerns.

Customers Who Bought This Also Bought