Serpin B5/Maspin Antibody (305339) [Alexa Fluor® 750]

• Reactivity: Hu
• Applications: WB, IP, KO
• Clone: 305339
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 750

Serpin B5/Maspin Antibody (305339) [Alexa Fluor® 750] Summary

• Immunogen: E. coli-derived recombinant human Serpin B5
  Met1-Pro375
  Accession # P36952
• Specificity: Detects human Serpin B5/Maspin in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross‑reactivity with recombinant human Serpin A5, B6, B8 or B9 is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Rat
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Knockout Validated
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Serpin B5/Maspin Antibody (305339) [Alexa Fluor® 750]

• Maspin
• Peptidase inhibitor 5
• PI5
• PI-5
• PI5protease inhibitor 5 (maspin)
• serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5
• Serpin B5
• serpin peptidase inhibitor, clade B (ovalbumin), member 5

Background

Serpin B5, also known as Maspin, is a secreted member of the Serpin family although it has no known serine protease inhibitor activity. It is produced by mammary epithelial cells and functions as a tumor suppressor. Serpin B5 is a valuable biomarker of tumor progression and overall prognosis. The amino acid sequence of human Serpin B5 is 99%, 92%, 89%, 88% and 64% identical to that of chimpanzee, dog, mouse, rat and chicken.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.