SERCA1 ATPase Antibody (SR1006) - BSA Free

Western Blot: SERCA1 ATPase Antibody (SR1006) [NBP3-22005] - Western blot analysis using NBP3-22005 in human fetal muscle lysate.

• Reactivity: Hu
• Applications: WB, IHC, IP
• Clone: SR1006
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

SERCA1 ATPase Antibody (SR1006) - BSA Free Summary

• Description: Novus Biologicals Rabbit SERCA1 ATPase Antibody (SR1006) - BSA Free (NBP3-22005) is a recombinant monoclonal antibody validated for use in IHC, WB and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human SERCA1 ATPase (Uniprot #: O14983)
• Specificity: Detects endogenous levels of total SERCA1 ATPase
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: ATP2A1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50-1:200
  • Immunoprecipitation 1:50
  • Western Blot 1:1000-1:5000
• Theoretical MW: 100 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.4, 150mM NaCl, 50% glycerol.
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for SERCA1 ATPase Antibody (SR1006) - BSA Free

• ATP2A
• ATP2A1
• ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
• Calcium pump 1
• Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletalmuscle isoform
• EC 3.6.3
• EC 7.2.2.10
• Endoplasmic reticulum class 1/2 Ca(2+) ATPase
• sarcoplasmic/endoplasmic reticulum calcium ATPase 1
• SERCA1 ATPase
• SERCA1
• SERCA1EC 3.6.3.8
• SR Ca(2+)-ATPase 1

Background

SERCA1 ATPase encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in two transcript variants encoding different isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ATP2A1