SERCA1 ATPase Antibody (SR1006)

Images

 
Western Blot: SERCA1 ATPase Antibody (SR1006) [NBP3-22005] - Western blot analysis using NBP3-22005 in human fetal muscle lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IP
Clone
SR1006
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

SERCA1 ATPase Antibody (SR1006) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthesized peptide derived from human SERCA1 ATPase (Uniprot #: O14983)
Specificity
Detects endogenous levels of total SERCA1 ATPase
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
ATP2A1
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50-1:200
  • Immunoprecipitation 1:50
  • Western Blot 1:1000-1:5000
Theoretical MW
100 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.4, 150mM NaCl, 50% glycerol.
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for SERCA1 ATPase Antibody (SR1006)

  • ATP2A
  • ATP2A1
  • ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
  • Calcium pump 1
  • Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletalmuscle isoform
  • EC 3.6.3
  • EC 7.2.2.10
  • Endoplasmic reticulum class 1/2 Ca(2+) ATPase
  • sarcoplasmic/endoplasmic reticulum calcium ATPase 1
  • SERCA1 ATPase
  • SERCA1
  • SERCA1EC 3.6.3.8
  • SR Ca(2+)-ATPase 1

Background

SERCA1 ATPase encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in two transcript variants encoding different isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SERCA1 ATPase Antibody (NBP3-22005) (0)

There are no publications for SERCA1 ATPase Antibody (NBP3-22005).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for SERCA1 ATPase Antibody (NBP3-22005) (0)

There are no reviews for SERCA1 ATPase Antibody (NBP3-22005). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for SERCA1 ATPase Antibody (NBP3-22005) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional SERCA1 ATPase Products

Research Areas for SERCA1 ATPase Antibody (NBP3-22005)

Find related products by research area.

Blogs on SERCA1 ATPase.

Mending a Broken Heart: New SERCA2 Gene Therapy Fights Heart Disease
While many of the proteins on our antibody database are studied in relation to their expression in diseases; others become therapies in their own right. This is the case with SERCA2 (Sarcoplasmic reticulum Calcium-ATPase 2 pump), which recently hit th...  Read full blog post.

mFluor Violet Conjugated Antibodies

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our SERCA1 ATPase Antibody (SR1006) and receive a gift card or discount.

Bioinformatics

Gene Symbol ATP2A1