Septin-6 Antibody - BSA Free

Staining of human skeletal muscle shows negative positivity in myocytes as expected.

Staining of human small intestine shows strong cytoplasmic-membranous positivity in glandular cells.

Staining of human lymph node shows strong cytoplasmic-membranous positivity in non-germinal center cells and germinal center cells.

Staining of human testis shows moderate cytoplasmic positivity in Leydig cells.

Analysis in human cell line SH-SY5Y.

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Septin-6 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Septin-6 Antibody - BSA Free (NBP1-89626) is a polyclonal antibody validated for use in IHC and WB. Anti-Septin-6 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: LGKSTLMDTLFNTKFEGEPATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSEL
• Predicted Species: Rat (95%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SEPTIN6
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:2500 - 1:5000
  • Immunohistochemistry-Paraffin 1:2500 - 1:5000
  • Western Blot 0.04-0.4 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  Septin-6 Protein (NBP1-89626PEP)

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 29229294).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Septin-6 Antibody - BSA Free

• KIAA0128SEP2septin 2
• MGC16619
• MGC20339
• SEPT2
• septin 6
• septin-6

Background

The Septin 6 gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint assoc

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Septin-6 Antibody (NBP1-89626)(1)

Publication using NBP1-89626

• Coulombe K, Kerdiles O, Tremblay C et al. Impact of DHA intake in a mouse model of synucleinopathy. Exp. Neurol. 2017-12-08 [PMID: 29229294] (Mouse)

Bioinformatics

• Gene Symbol: SEPTIN6