SCD-1 Antibody (428208) [Alexa Fluor® 350]

• Applications: WB
• Clone: 428208
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 350

SCD-1 Antibody (428208) [Alexa Fluor® 350] Summary

• Immunogen: S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse SCD-1
  Met1-Ser355
  Accession # P13516
• Specificity: Detects mouse SCD-1 in direct ELISAs and Western blots.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Purity Statement: Protein A or G purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

Stearoyl-CoA Desaturase 1 (SCD-1) is a four-transmembrane endoplasmic reticulum protein that is a rate-limiting enzyme in the formation of triglycerides, cholesteryl esters and phospholipids from saturated fatty acids. Its expression in adipose and liver is enhanced by insulin and certain dietary sugars and fats, and down‑regulated by TNF-alpha . SCD-1 is one of four iron-containing murine stearoyl-CoA desaturases that share 79‑88% aa identity. The 355 aa, predicted 41 kDa mouse SCD-1 shares 92% and 84% aa identity with rat and human SCD-1, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.